{"id":6925,"date":"2021-04-09T22:06:56","date_gmt":"2021-04-09T20:06:56","guid":{"rendered":"https:\/\/wpdev.tastro.eu\/?p=6925"},"modified":"2026-03-11T14:53:04","modified_gmt":"2026-03-11T13:53:04","slug":"kanabinoidi-so-glavne-spojine-v-konoplji","status":"publish","type":"post","link":"https:\/\/wpdev.tastro.eu\/si\/kanabinoidi-so-glavne-spojine-v-konoplji\/","title":{"rendered":"Kaj so kanabinoidi in kako delujejo?"},"content":{"rendered":"\t\t
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O kanabinoidih<\/h2>\n\n

Kanabinoidi so glavna skupina spojin, ki so prisotni v konoplji. So heterogena skupina spojin, katerih skupna zna\u010dilnost je, da se ve\u017eejo na kanabinoidne receptorje v telesu. V osnovi jih delimo na tri skupine glede na njihov izvor (endokanabinoidi, fitokanabinoidi in sinteti\u010dni kanabinoidi).<\/p>\n\n

Endokanabinoidi nastajajo v telesu, fitokanabinoidi nastajajo v rastlinah, sinteti\u010dne kanabinoide pa se sintezno pripravi v laboratoriju.<\/p>\n\n

Endokanabinoidi so \u010dloveku lastni kanabinoidi in jih na\u0161e telo proizvaja v \u017eiv\u010dnih celicah ter slu\u017eijo kot signalne molekule. Na\u0161e celice vsebujejo tudi kanabinoidne receptorje (CB1 in CB2), ki zaznavajo koli\u010dino oz. koncentracijo kanabinoidov v celicah. Tudi na\u0161i mo\u017egani zaznavajo spremembe v koncentraciji kanabinoidov v na\u0161em telesu ter se posledi\u010dno temu primerno tudi odzovejo.<\/p>\n\n

Fitokanabinoidi, kot \u017ee ime pove, so rastlinskega izvora in so po kemijski strukturi podobni endokanabinoidom in v na\u0161em telesu aktivirajo iste receprotorje (CB1 in CB2) kot endokanabinoidi. V svetu je poznanih \u017ee ve\u010d kot 140 kanabinoidov, med fitokanabinoidi sta tretnutno najbolj raziskana CBD in THC, zadnje raziskave pa vklju\u010dujejo tudi druge kanabinoide (CBN, CBC, CBG, itd).<\/p>\n\n

Sinteti\u010dne kanabinoide se s kemijsko sintezo pripravi v laboratoriju in so prisotni v veliki ve\u010dini farmacevtskih pripravkov. Raziskave so pokazale, da so v primerjavi z naravnimi oblikami kanabinoidov bistveno manj u\u010dinkoviti.<\/p>\n\n

Kanabinoide delimo v ve\u010d skupin, znotraj skupin pa najdemo ve\u010dje \u0161tevilo razli\u010dnih kanabinoidov.<\/p>\n\n

Ve\u010dina kanabinoidov nima psihoaktivnih u\u010dinkov, delujejo pozitivno na na\u0161e telo in imunski sistem. Kanabinoidi v kombinaciji s terpeni delujejo sinergijsko, s \u010dimer se njihov efekt pove\u010da (\u00bbentourage efekt\u00ab). Najbolj poznana in raziskana sta kanabinoida kanabinol (CBD), ki je psihoneaktiven kanabinoid in tetrahidrokanabinol (THC), ki je eden redkih kanabinoidov s psihoaktivnim efektom. Vedno ve\u010d raziskav je usmerjenih v raziskovanje sinergijskih u\u010dinkov kanabinoidov in terpenov.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"CBD\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Strukture glavnih kanabinoidov<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\"d8-THC-d8-tetrahidrokanabinol\"
d8-THC-d8-tetrahidrokanabinol<\/figcaption><\/figure><\/div>
\"d9-THC-d9-tetrahidrokanabinol\"
d9-THC-d9-tetrahidrokanabinol<\/figcaption><\/figure><\/div>
\"CBT-Kanabitriol\"
CBT-Kanabitriol<\/figcaption><\/figure><\/div>
\"CBL-Kanabiciklol\"
CBL-Kanabiciklol<\/figcaption><\/figure><\/div>
\"CBN-Kanabinol\"
CBN-Kanabinol<\/figcaption><\/figure><\/div>
\"CBE-Kanabielsoin\"
CBE-Kanabielsoin<\/figcaption><\/figure><\/div>
\"CBG-Kanabigerol\"
CBG-Kanabigerol<\/figcaption><\/figure><\/div>
\"CBDA-Kanabidiolna-kislina\"
CBDA-Kanabidiolna-kislina<\/figcaption><\/figure><\/div>
\"CBC-Kanabikromen\"
CBC-Kanabikromen<\/figcaption><\/figure><\/div>
\"CBD-Kanabidiol\"
CBD-Kanabidiol<\/figcaption><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t
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Kanabinoidi v naravi<\/h2>\n

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Konoplja je edinstvena rastlina na zemlji, v kateri nastajajo kanabinoidi, najdemo pa jih tudi v nekaterih drugih rastlinah, za katere je znano da blagodejno vplivajo na ne\u0161e telo in po\u010dutje. Kanabinoide v manj\u0161ih koncentracijah najdemo v ameri\u0161kem slamniku, brazilski kre\u0161i, slamniku (strawflower) in nekaterih drugih.<\/p>\n

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Ker nastajajo v rastlini, jim pravimo\u00a0fitokanabinoidi<\/strong><\/em>. V rastlinah so fitokanabinoidi predvsem v kislinski obliki. V na\u0161em telesu nastajajo endokanabinoidi in so v nekislinski obliki. Rastlinski fitokanabinoidi se s postopkom dekarboksilacije pretvorijo v nekislinske\/aktivne kanabinoide.<\/p>\n

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V svetu najbolj poznan kanabinoid, CBD \u2013 kanabidiol, kakor tudi ostali kanabinodi, se v konoplji nahajajo v kislinski obliki (CBDA, THCA, CBGA, itd), v manj\u0161em dele\u017eu pa so prisotni kanabinodi tudi v nekislinski\/aktivni obliki (CBD, CBG, THC, itd).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Kako si lahko pomagamo?<\/h2>\n

V na\u0161em podjetju veliko \u010dasa namenimo raziskavam na podro\u010dju zdravilnih rastlin, predvsem konoplje in njenih ekstraktov. V kolikor pove\u017eemo prave rastline v pravo sinergijo, se lahko njihov efekt bistveno pove\u010da. Z na\u0161im lastnim znanjem smo razvili Konopljine CBD kapljice, ki imajo razli\u010den u\u010dinek delovanja glede na te\u017eave, s katerimi se vsakodnevno srere\u010dujemo. Na\u0161e izdelke nam pomagajo razvijati strokovnjaki iz razli\u010dnih podro\u010dij znotraj podjetja WidLab d.o.o.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\tNe spreglejte\t\t\t\t<\/p>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"CBD\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"Sleeper,\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tV trgovino<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tPreberi ve\u010d<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Kanabinoidi so glavna skupina spojin, ki so prisotni v konoplji. So heterogena skupina spojin, katerih skupna zna\u010dilnost je, da se ve\u017eejo na kanabinoidne receptorje v telesu. V osnovi jih delimo na tri skupine glede na njihov izvor (endokanabinoidi, fitokanabinoidi in sinteti\u010dni kanabinoidi).<\/p>\n","protected":false},"author":2,"featured_media":7433,"comment_status":"closed","ping_status":"open","sticky":false,"template":"elementor_theme","format":"standard","meta":{"footnotes":""},"categories":[69,56],"tags":[59,65,57],"class_list":["post-6925","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kanabinoidi","category-konoplja","tag-cbd","tag-kanabinoidi","tag-konoplja"],"_links":{"self":[{"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/posts\/6925","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/comments?post=6925"}],"version-history":[{"count":42,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/posts\/6925\/revisions"}],"predecessor-version":[{"id":10317,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/posts\/6925\/revisions\/10317"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/media\/7433"}],"wp:attachment":[{"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/media?parent=6925"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/categories?post=6925"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpdev.tastro.eu\/si\/wp-json\/wp\/v2\/tags?post=6925"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}